Meniere’s Disease: The First Step Towards the Right Direction.

Meniere’s disease is a very aggressive disorder that affects our organs of audition (hearing) and equilibrium, the cochlea (contains the organ of corti, and produces nerve impulses from the vibrations of sounds) and vestibule of the inner ear, respectively. Persons suffering from Meniere’s disease will have symptoms such as attacks of dizziness (vertigo), ringing of the ears (tinnitus), and hearing loss. This happens because the amount of fluid, endolymph, in the labyrinth increases which increases pressure on the delicate organs of the inner ear. Meniere’s disease can happen at any age but is most common in older adults between the ages of 40-60 years old. This disease usually only effects one ear and over a period of several years can cause deafness.

There are cochlear implants to replace lost hearing that results from inner ear damage, however, for people who suffer with balance disorders, there has not been any treatments. Christopher Phillips and his colleagues from the University of Washington developed a vestibular prosthesis that will give an electrical stimulation in the semi-circular canals’ fluid of the ear. When this happens the fluid manipulates the brain into thinking the body is swaying or moving in a particular direction. When the brain is tricked it causes a compensatory postural reflex that will stabilize the body posture which helps to restore balance and stop the dizzy feeling.

This discovery is actually pretty cool and cleaver by manipulating the brain. This is clearly a first step into finding a cure or way to help with a balance disorder resulting from an inner ear disease. It will help people who suffer from this disease recover their balance and be able to function in daily life properly. I am sure that the people who suffer from this disease is very thrilled that there may be a stop to their complications.

  1. http://www.sciencedaily.com/releases/2013/06/130613104137.htm
  2. A&P class lecture text

Scoliosis Gene Found

Scoliosis is an abnormal sideways curve of the spinal cord. The word “scolio” means crooked. When you look at a person from the back that does not have scoliosis their spinal cord and back appears to be in a straight line. However, when you look at a person with scoliosis there spinal cord and upper back makes a “c” shape. Scoliosis is a vertebral deformity that you are born with.
Dr. Ikuyo Kou and Dr. Shiro Ikegawa did a study in Japan at the Riken center to see if or what genetic factors are associated with scoliosis. Their study consisted of 1,819 Japanese individuals that were diagnosed with scoliosis compared to 25,939 Japanese individuals who did not have scoliosis. They compared the genes of these individuals who participated in their study and found that on chromosome 6 there was a gene associated with scoliosis. Researchers believe that the gene is, GPR126, and is highly expressed in cartilage and that leads to delayed bone growth and tissue formation in delevoping spine.
This research can greatly affect people will scoliosis. As of now, one method of “treatment” is wearing a back brace which is supposed to keep the curve from progressing any further. Another method would be having surgery, which is, a method of going into the vertebral column and attaching metal rods that are supposed to force the spinal cord to straighten. Both of these methods help but I am sure people who have scoliosis would like to have more options of treatment and that can be achieved in the future with this amazing discovery the Riken center made.

                                                                                                                  Work Citied
RIKEN. “Gene associated with adolescent idiopathic scoliosis identified.” ScienceDaily, 12 May 2013. Web. 3 Oct. 2013.                     http://www.sciencedaily.com/releases/2013/05/130512140943.htm
Tortora G.J. and B. Derrickson. 2012. Principles of Anatomy and Physiology. 13th ed., John Wiley and Sons